Interesting finding just out!
Journal of Clinical Oncology (Feb 3rd online version)
This study is testing itraconazole's (a drug prescribed fro common fungal infections) effectiveness in treating patients with multiple basal cell carcinoma tumors. This drug appears to disable the Hedgehog signaling pathway. The drug is given in the normal dosage prescribed fro fungal infections.
This does not appear to be as effective as vismodegib on advanced tumors, but it may be useful in smaller tumors and much less expensive ($20/day vs. $250/day).
This could be an interesting and helpful drug to augment basal cell cancer.